Sermorelin is a synthetic version of bio-identical hormone, which has been manufactured to help in stimulating the production and secretion of growth hormone releasing hormone or GHRH from the hypothalamus. Human growth hormone is important in the growth and development of children and adults as well. Sermorelin is comprised of twenty-nine amino acids, which works by replacing growth hormone releasing hormone, which has 44 amino acids, this triggers the release of growth hormone. In most instances, the treatment is used to stimulate growth in children who have deficiencies in the production of GHRH and on the other hand, it is sought by people who want to reverse or slow down the aging process. Just like human growth hormones Sermorelin accentuates the production of new myocytes, the production of new muscle cells is vital for people seeking to improve their strength and stamina.
The hormone causes reduction of fat within the body this is a beneficial feature especially in people who want to lose weight. Moreover, studies show that Sermorelin improves the body’s immune system and makes the heart stronger. Sermorelin helps in repairing muscle cells, healing wounds much quicker, in addition, it is known to induce better sleep. Good sleep is equivalent to energetic and rejuvenated person in the morning moreover the moods are improved. On metabolic front Sermorelin helps the body in retaining calcium an essential mineral in bone strength and formation. Bone density is important especially in children and elderly population, low calcium levels causes weak bones and conditions such as rickets in children and osteomalacia in adults. Moreover, human growth hormone will help the elderly stimulate the production of proteins and this aid in healing and optimal functioning of internal organs.
Growth hormone replacement therapy includes the use of recombinant human growth hormone that has been embraced by many medical practitioners for its effectiveness in opposing somatic senescence. The use of GH secretagogues promotes better brain function and pituitary health. The hormone accentuates the production of growth factors. Sermorelin have a positive feedback on the function of the pituitary gland and it promotes a youthful look in adult population. Unlike other synthetic hormones, Sermorelin stimulates the production of bioactive hormone IGF-1 from the liver, the hormones binds specifically to receptors in the pituitary glands and promotes the production and secretion of endogenous growth hormone. Somatostatin works against the hormone, however with sufficient amount of the hormone the effectiveness of the hormone is not affected. Tachphylaxis can be avoided by the use of Sermorelin-induced release of the growth hormone.
Research shows that the hormone stimulates the transcription of a pituitary gene hGH messenger RNA and this increases pituitary reserve, which preserves more growth hormone neuroendocrine axis. Pituitary recrudescence resulting from the hormone is essential in slowing down the cascade of hypophyseal hormonal failure, which mostly occurs to ageing population. Sermorelin was developed in the 70s and consequent research and studies have been done to determine its safety, effectiveness, and efficiency in treating growth related problems. Human growth hormone is released during rapid eye movement sleep, in some instances it is released in small quantities during the day. The hormone is vital in preserving tissues, organs, joints, ligaments without it the body will succumb to symptoms of age related problems.